Incidence of Nocturnal Desaturation While Breathing Oxygen in COPD Patients Undergoing Long-term Oxygen Therapy

摘要: Study objective It is suggested that oxygen flow be increased by 1 L/min during sleep in COPD patients undergoing long-term therapy (LTOT) order to avoid nocturnal desaturations. The purpose of this study was investigate the occurrence desaturations while breathing receiving LTOT. Setting Inpatient/university hospital. Patients We studied 82 consecutive patients. Their functional characteristics were as follows (mean ± SD): FVC, 2.15 0.69 L; FEV , 0.87 0.33 Pa o 2 51.6 5 mm Hg; and co 47 8 Hg. Measurements Overnight pulse oximetry (PO) performed twice: (1) air (2) supplemental assuring satisfactory diurnal resting oxygenation breathing, 67 6 mean arterial saturation [Sa ] 93%). Results PO showed a overnight Sa 82.7 6.7%. spent 90% recording time with an 94.4 2.1%, 30% night 87.1 4.5%, on (p Conclusions conclude about half LTOT need sleep. both hypercapnia (Pa ≥ 45 Hg)