C4d: a marker for hepatic transplant rejection.

作者: R. Lorho , B. Turlin , N. Aqodad , N. Triki , A.S. de Lajarte-Thirouard

DOI: 10.1016/J.TRANSPROCEED.2006.06.120

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摘要: Abstract Background Acute rejection is still a common complication of hepatic transplantation. The diagnosis, based on the histological examination graft, may be difficult to confirm in setting combined hepatitis C virus infection. presence C4d portal capillaries could facilitate differentiation between acute and relapsed C. deposit provides evidence activation humoral immunity. To attempt this hypothesis, we searched for posttransplant biopsies. Methods Thirty-six biopsies from 34 patients were analyzed retrospectively. samples had been requested one following reasons: suspected rejection, infection, or systematic check-up 1 year after transplant. Results expression was classified as (33%) chronic (100%). never detected event recurrent infection without rejection. Conclusion These results, which are comparable recently published data, give credence theory that used marker

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