How cells read TGF-beta signals.

作者: Joan Massagué

DOI: 10.1038/35043051

关键词:

摘要: Cell proliferation, differentiation and death are controlled by a multitude of cell-cell signals, loss this control has devastating consequences. Prominent among these regulatory signals is the transforming growth factor-beta (TGF-beta) family cytokines, which can trigger bewildering diversity responses, depending on genetic makeup environment target cell. What networks cell-specific molecules that mould TGF-beta response to each cell's needs?

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