Data mining using the Catalogue of Somatic Mutations in Cancer BioMart.

作者: R. Shepherd , S. A. Forbes , D. Beare , S. Bamford , C. G. Cole

DOI: 10.1093/DATABASE/BAR018

关键词:

摘要: Catalogue of Somatic Mutations in Cancer (COSMIC) (http://www.sanger.ac.uk/cosmic) is a publicly available resource providing information on somatic mutations implicated human cancer. Release v51 (January 2011) includes data from just over 19 000 genes, 161 787 coding and 5573 gene fusions, described more than 577 000 tumour samples. COSMICMart (COSMIC BioMart) provides flexible way to mine these combine with other biological relevant sets. This article describes the COSMIC along examples how successfully integrate sets using COSMICMart. Database URL: http://www.sanger.ac.uk/genetics/CGP/cosmic/biomart/martview/

参考文章(20)
S.A. Forbes, G. Bhamra, S. Bamford, E. Dawson, C. Kok, J. Clements, A. Menzies, J.W. Teague, P.A. Futreal, M.R. Stratton, The Catalogue of Somatic Mutations in Cancer (COSMIC). Current protocols in human genetics. ,vol. 57, ,(2008) , 10.1002/0471142905.HG1011S57
Ultan McDermott, Sreenath V. Sharma, Jeffrey Settleman, High-throughput lung cancer cell line screening for genotype-correlated sensitivity to an EGFR kinase inhibitor. Methods in Enzymology. ,vol. 438, pp. 331- 341 ,(2008) , 10.1016/S0076-6879(07)38023-3
Audrey Petitjean, Ewy Mathe, Shunsuke Kato, Chikashi Ishioka, Sean V. Tavtigian, Pierre Hainaut, Magali Olivier, Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Human Mutation. ,vol. 28, pp. 622- 629 ,(2007) , 10.1002/HUMU.20495
Pasi A. Jänne, Nathanael Gray, Jeff Settleman, Factors underlying sensitivity of cancers to small-molecule kinase inhibitors Nature Reviews Drug Discovery. ,vol. 8, pp. 709- 723 ,(2009) , 10.1038/NRD2871
Sreenath V. Sharma, Daniel A. Haber, Jeff Settleman, Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents Nature Reviews Cancer. ,vol. 10, pp. 241- 253 ,(2010) , 10.1038/NRC2820
D. Croft, G. O'Kelly, G. Wu, R. Haw, M. Gillespie, L. Matthews, M. Caudy, P. Garapati, G. Gopinath, B. Jassal, S. Jupe, I. Kalatskaya, S. Mahajan, B. May, N. Ndegwa, E. Schmidt, V. Shamovsky, C. Yung, E. Birney, H. Hermjakob, P. D'Eustachio, L. Stein, Reactome: a database of reactions, pathways and biological processes Nucleic Acids Research. ,vol. 39, pp. 691- 697 ,(2011) , 10.1093/NAR/GKQ1018
D. W. Parsons, S. Jones, X. Zhang, J. C.-H. Lin, R. J. Leary, P. Angenendt, P. Mankoo, H. Carter, I-M. Siu, G. L. Gallia, A. Olivi, R. McLendon, B. A. Rasheed, S. Keir, T. Nikolskaya, Y. Nikolsky, D. A. Busam, H. Tekleab, L. A. Diaz, J. Hartigan, D. R. Smith, R. L. Strausberg, S. K. N. Marie, S. M. O. Shinjo, H. Yan, G. J. Riggins, D. D. Bigner, R. Karchin, N. Papadopoulos, G. Parmigiani, B. Vogelstein, V. E. Velculescu, K. W. Kinzler, An Integrated Genomic Analysis of Human Glioblastoma Multiforme Science. ,vol. 321, pp. 1807- 1812 ,(2008) , 10.1126/SCIENCE.1164382
R Gaspar Aparicio, D Gomez, I Coterillo Coz, D Wojcik, DataBase on Demand Journal of Physics: Conference Series. ,vol. 396, pp. 052034- ,(2012) , 10.1088/1742-6596/396/5/052034