作者: Zehra Akpınar , Serhat Tokgöz , Hakkı Gökbel , Nilsel Okudan , Faruk Uğuz
DOI: 10.1016/J.PSYCHRES.2007.11.022
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摘要: Abstract The association of nocturnal serum melatonin levels was investigated in acute multiple sclerosis (MS) patients with major depression (MD). sample comprised 13 MD and 12 no psychiatric disorders admitted to our clinic due MS attacks. Psychiatric evaluation performed the Structured Clinical Interview for DSM-IV (SCD-I). level depressive symptoms assessed Beck Depression Scale (BDS). Blood samples were taken from determine at 03.30h 10.00h before steroid treatment started. Melatonin determined using ELISA test. Nocturnal (21.2 ± 17.1 pg/ml) significantly lower than those (51.5 ± 18.3 pg/ml) without MD. A significant negative correlation found between BDS scores levels. These findings suggest that a deficiency may be among factors involved occurence patients.