Molecular Determinants in the Biology of Liver Metastasis

作者: Robert Radinsky , Lee M. Ellis

DOI: 10.1016/S1055-3207(18)30378-8

关键词:

摘要: Metastasis is a highly selective process whereby only cells that express the necessary phenotype are capable of completing all steps in metastatic process. In addition, host organ interactions with tumor cell play crucial role formation viable metastases. The liver frequent site metastasis owing to both anatomic and biologic determinants. this article, authors have provided readers better understanding biology metastases molecular events leading phenotype. This information essential if new therapeutic approaches be developed treat disease.

参考文章(37)
Emilio Barbera-Guillem, Isabel Smith, Leonard Weiss, Cancer-cell traffic in the liver. I. Growth kinetics of cancer cells after portal-vein delivery. International Journal of Cancer. ,vol. 52, pp. 974- 977 ,(1992) , 10.1002/IJC.2910520624
E. Buchdunger, U. Trinks, H. Mett, U. Regenass, M. Muller, T. Meyer, E. McGlynn, L. A. Pinna, P. Traxler, N. B. Lydon, 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 2334- 2338 ,(1994) , 10.1073/PNAS.91.6.2334
J. L. Camps, S. M. Chang, T. C. Hsu, M. R. Freeman, S. J. Hong, H. E. Zhau, A. C. von Eschenbach, L. W. Chung, Fibroblast-mediated acceleration of human epithelial tumor growth in vivo Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 75- 79 ,(1990) , 10.1073/PNAS.87.1.75
Leland W. K. Chung, Fibroblasts are critical determinants in prostatic cancer growth and dissemination. Cancer and Metastasis Reviews. ,vol. 10, pp. 263- 274 ,(1991) , 10.1007/BF00050797
Josée Coulombe, Guy Pelletier, Gangliosides and organ-specific metastatic colonization International Journal of Cancer. ,vol. 53, pp. 104- 109 ,(1993) , 10.1002/IJC.2910530120
Angels Fabra, Motowo Nakajima, Corazon D. Bucana, Isaiah J. Fidler, Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice. Differentiation. ,vol. 52, pp. 101- 110 ,(1992) , 10.1111/J.1432-0436.1992.TB00504.X
Isaiah J. Fidler, Charles M. Blach, The biology of cancer metastasis and implications for therapy Current Problems in Surgery. ,vol. 24, pp. 137- 209 ,(1987) , 10.1016/0011-3840(87)90002-5
I. J. Fidler, R. Radinsky, Genetic Control of Cancer Metastasis Journal of the National Cancer Institute. ,vol. 82, pp. 166- 168 ,(1990) , 10.1093/JNCI/82.3.166
Judah Folkman, What is the evidence that tumors are angiogenesis dependent Journal of the National Cancer Institute. ,vol. 82, pp. 4- 7 ,(1990) , 10.1093/JNCI/82.1.4
Shin Fujita, Hiroko Suzuki, Masao Kinoshita, Setsuo Hirohashi, Inhibition of Cell Attachment, Invasion and Metastasis of Human Carcinoma Cells by Anti-integrin β1 Subunit Antibody Japanese Journal of Cancer Research. ,vol. 83, pp. 1317- 1326 ,(1992) , 10.1111/J.1349-7006.1992.TB02764.X