作者: Robert Radinsky , Lee M. Ellis
DOI: 10.1016/S1055-3207(18)30378-8
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摘要: Metastasis is a highly selective process whereby only cells that express the necessary phenotype are capable of completing all steps in metastatic process. In addition, host organ interactions with tumor cell play crucial role formation viable metastases. The liver frequent site metastasis owing to both anatomic and biologic determinants. this article, authors have provided readers better understanding biology metastases molecular events leading phenotype. This information essential if new therapeutic approaches be developed treat disease.