作者: AJ Cochran , H-F Lu , P-X Li , R Saxton , D-R Wen
DOI: 10.1097/00008390-199310000-00004
关键词:
摘要: S-100 protein, extracted from bovine brain, is the first described of modern generation marker molecules for melanocytic tumours. Despite observation that many different types cells express detection molecule in tumour appropriate clinical and pathological circumstances a widely used effective adjunct to determination melanocytic. Antibodies protein are best deployed as part package includes antibodies other melanoma-associated epitopes (HMB-45, NKI-C3/Beteb), cytokeratins common leukocyte antigen. may also increase accuracy melanoma staging permit small numbers metastatic not detectable by conventional histology. Future applications will probably include wider use monomers (alpha beta) quantification body fluids tissues.