作者: Marco Nassisi , Elmira Baghdasaryan , Tudor Tepelus , Samuel Asanad , Enrico Borrelli
DOI: 10.1371/JOURNAL.PONE.0207638
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摘要: Purpose To evaluate the topographic distribution of choriocapillaris (CC) flow deficits in a population healthy subjects. Methods Using swept-source optical-coherence tomography angiography (SS-OCTA) device, two repeated volume 6 x mm and 3 scans were acquired subjects at Doheny—UCLA Eye Centers. The en-face CC angiogram was binarized analyzed for percentage (FD%) using grid progressive, concentric rings covering circular area with diameter 2.5 (in scans) 5 scans). FD% each ring plotted against distance from fovea. linear trendline resulting curve slope (m) intercept (q) computed. Results Seventy-five eyes 75 enrolled divided into three subgroups based on age (year ranges: 21–40, 41–60 61–80). For entire cohort within subgroup, there significant association between fovea both 3X3 6X6 scans, increasing closer proximity to foveal center. Age predictor m q scan patterns, older showing steeper slope. Conclusions In SS-OCTA images, varies age. In particular, tends decrease towards periphery, decline advancing These normal trends may need be accounted future studies disease.