Sequential Imaging and Volumetric Analysis of an Intracerebral C6 Glioma by Means of a Clinical MRI System

作者: Frank A. Raila , Alfred P. Bowles , Eddie Perkins , Allen Terrell

DOI: 10.1023/A:1006285800794

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摘要: In this study, using high resolution coils; implanted growing rat brain tumors were imaged sequentially with 3-D measurements generated by means of a clinical magnetic resonance imaging system (CMRI) and commercially available wrist coil. Ten female Sprague–Dawley rats used, eight C6 glioma cells two served as controls. The images that used for the three-dimensional (3-D) obtained from T1 weighted post contrast sequences. A computer work station image analysis software was to generate tumor volumes. addition studies mouse included see if would be adequate very small brains. Six had growth after transplantation did not have any growth, however, their similar controls animals. Tumor volumes varied widely among rats. number no direct relationship developing This study demonstrates can CMRI coil which is capable at same time or even brain. able ability volume over has potential animal research.

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