The epidemiology of Norovirus in the Middle East and North Africa (MENA) region: a systematic review.

摘要: Norovirus (NoV) is considered the second leading cause of viral acute gastroenteritis (AGE). To our knowledge, there are no systematic reviews assessing role NoV in AGE Middle East and North Africa (MENA) region. Consequently, we conducted an extensive literature review on articles studying 24 countries MENA region during past 15 years (2000-2015). The methods reporting were set according to 2015 PRISMA-P based elements from international prospective register (PROSPERO). We retrieved 38 studies meeting predefined inclusion criteria used extract full data. Studies 15 out reported infection rates ranged between 0.82% 36.84%. majority clinical observational mainly among children. Participants recruited in- outpatient clinics. was all year round with peaks observed cold months. GII.4 predominant genotype detected stool participants as by 16 25 (64%). Overall, increasing recognition important causative agent across age groups Further needed assess national regional burden different groups, its molecular diversity seasonal variability.