Characteristic histologic triad in liver adjacent to metastatic neoplasm.
作者： MICHAEL A. GERBER , SWAN N. THUNG , HENRY C. BODENHEIMER , BARBARA KAPELMAN , FENTON SCHAFFNER
DOI: 10.1111/J.1600-0676.1986.TB00273.X
关键词:
摘要: — More than 25% of undirected percutaneous liver needle biopsies that are performed in search metastatic neoplasms yield false negative specimens. Often, however, histologic changes observed the adjacent to space-occupying lesions due focal obstruction bile and blood flow. These alterations were defined by semi-quantitative evaluation 20 biopsy specimens with neoplasms, revealed a characteristic triad consisting proliferated abnormal ductules, polymorphonuclear leukocytes edematous portal tracts sinusoidal dilatation. When 15 patients this combination alterations, but without malignant cells specimens, investigated prospectively, 13 (87%) found have hepatic metastases. Therefore, observation described here should lead continued for liver.
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