Autoimmunity vs. cancer: predator vs. alien?
作者： Christian Berens , Kirsten Lauber , Martin Herrmann
DOI: 10.3109/08916934.2013.787687
关键词:
摘要: "The enemy of my is friend." According to this motto, the human protagonists in Paul W. S. Anderson's science-fiction movie "Alien vs. Predator" (2004) solidarize with a predator order fight aliens. Can ancient and simple logic be transferred field oncology cancer immunotherapy? we utilize mechanisms known from context autoimmunity cancer? Here, summarize immune cell-mediated detection danger damage, central peripheral tolerance, immunoregulation privilege--processes deregulated autoimmunity. We discuss them special regard towards their misusage by tumors pathogens how they might instrumentalized anti-cancer immunotherapy.
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