Copper(I)-Catalyzed Heterocyclization of α-Acyl-α-alkynyl Ketene Dithioacetals: Synthesis of 3-Cyanofurans.
作者： Lianjie Wang , Xiaocui Liu , Mang Wang , Jun Liu
DOI: 10.1021/ACS.ORGLETT.6B00785
关键词:
摘要: A new method for the synthesis of 3-cyanofurans via Cu(I)-catalyzed heterocyclization α-acyl-α-alkynyl ketene dithioacetals in presence ammonium acetate has been developed. The procedure generates cyano moiety situ with as nitrogen source. Based upon experimental observations, a plausible reaction mechanism is proposed.
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