Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial–mesenchymal transition

作者: T Li , Z-C Zeng , L Wang , S-J Qiu , J-W Zhou

DOI: 10.1038/CGT.2011.29

关键词:

摘要: … tumor grew to the maximal diameter of 1.0–1.5 cm and was palpable, radiation port was designed on the basis of tumor location… allow tumor cells to metastasize and establish secondary …

参考文章(37)
Jan Gliemroth, Thomas Feyerabend, Christiane Gerlach, Hans Arnold, A. Jorge A. Terzis, Proliferation, migration, and invasion of human glioma cells exposed to fractionated radiotherapy in vitro. Neurosurgical Review. ,vol. 26, pp. 198- 205 ,(2003) , 10.1007/S10143-003-0253-1
So-Young Choi, Young Woo Park, Hyun-Chul Shin, Seon-Young Kim, Role of TMPRSS4 during cancer progression. Drug News & Perspectives. ,vol. 21, pp. 417- 423 ,(2008) , 10.1358/DNP.2008.21.8.1272135
Walter E. Laug, Peter A. Jones, Margaret A. Heisel, Stephen M. Stowe, Effects of X-Irradiation on Artificial Blood Vessel Wall Degradation by Invasive Tumor Cells Cancer Research. ,vol. 44, pp. 2441- 2445 ,(1984)
R. Daniel Bonfil, Oscar D. Bustuoabad, Raul A. Ruggiero, Roberto P. Meiss, Christiane D. Pasqualini, Tumor necrosis can facilitate the appearance of metastases. Clinical & Experimental Metastasis. ,vol. 6, pp. 121- 129 ,(1988) , 10.1007/BF01784843
Wei Ding, Hanning You, Hien Dang, Francis LeBlanc, Vivian Galicia, Shelly C. Lu, Bangyan Stiles, C. Bart Rountree, Epithelial-to-mesenchymal transition of murine liver tumor cells promotes invasion. Hepatology. ,vol. 52, pp. 945- 953 ,(2010) , 10.1002/HEP.23748
M. M. Javle, J. F. Gibbs, K. K. Iwata, Y. Pak, P. Rutledge, J. Yu, J. D. Black, D. Tan, T. Khoury, Epithelial-mesenchymal transition (EMT) and activated extracellular signal-regulated kinase (p-Erk) in surgically resected pancreatic cancer. Annals of Surgical Oncology. ,vol. 14, pp. 3527- 3533 ,(2007) , 10.1245/S10434-007-9540-3
Peter P. Lai, Carlos A. Perez, Mary Ann Lockett, Prognostic significance of pelvic recurrence and distant metastasis in prostate carcinoma following definitive radiotherapy International Journal of Radiation Oncology*Biology*Physics. ,vol. 24, pp. 423- 430 ,(1992) , 10.1016/0360-3016(92)91055-R
J. De Ruiter, S.J. Cramer, P. Lelieveld, L.M. Van Putten, Comparison of metastatic disease after local tumour treatment with radiotherapy or surgery in various tumour models European Journal of Cancer and Clinical Oncology. ,vol. 18, pp. 281- 289 ,(1982) , 10.1016/0277-5379(82)90047-5