Effects of negative air ions on activity of neural substrates involved in autonomic regulation in rats
作者： Satoko Suzuki , Shinya Yanagita , Seiichiro Amemiya , Yumi Kato , Natsuko Kubota
DOI: 10.1007/S00484-007-0143-2
关键词:
摘要: The neural mechanism by which negative air ions (NAI) mediate the regulation of autonomic nervous system activity is still unknown. We examined effects NAI on physiological responses, such as blood pressure (BP), heart rate (HR), and variability (HRV) well neuronal activity, in paraventricular nucleus hypothalamus (PVN), locus coeruleus (LC), ambiguus (NA), solitary tract (NTS) with c-Fos immunohistochemistry anesthetized, spontaneously breathing rats. In addition, we performed cervical vagotomy to reveal afferent pathway involved mediating regulation. significantly decreased BP HR, increased HF power HRV spectrum. Significant decreases positive nuclei PVN LC, enhancement expression NA NTS were induced NAI. After vagotomy, these responses not observed. These findings suggest that can modulate through inhibition LC activation neurons, might be mediated via vagus nerves.
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