Serum ferritin and transferrin saturation in Asians and Pacific Islanders.
作者： Emily L Harris , Christine E McLaren , David M Reboussin , Victor R Gordeuk , James C Barton
DOI: 10.1001/ARCHINTE.167.7.722
关键词:
摘要: Background Asians and Pacific Islanders in the Hemochromatosis Iron Overload Screening (HEIRS) Study had highest prevalence of elevated serum ferritin (SF) transferrin saturation (TS) levels, but to our knowledge, reasons for this have not been investigated. Methods Using multiple linear regression, we compared TS SF distributions 42 720 Asian, Islander, white HEIRS participants recruited through 5 field centers North America who did haveHFEC282YorH63Dalleles. Results Compared with their counterparts, Asian men a 69-ng/mL (155-pmol/L) higher adjusted mean level 3% (P Conclusion Higher levels persons or Island heritage may need be interpreted differently than whites, although biological basis clinical significance among are unclear.
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