Vanadium salts and the future treatment of diabetes
作者： Yoram Shechter , Assia Shisheva
DOI: 10.1016/0160-9327(93)90008-Q
关键词:
摘要: Until the discovery of insulin by Banting and Best in 1922, diabetes had a high mortality rate. Since then regular administration drug has brought it under control. Nevertheless is not an ideal drug, that to be injected because incidence resistance. There is, therefore, need for alternative forms treatment recent years interest centred on possibilities vanadium salts.
elsevier.com
sci-hub.se 参考文章(21)
F G Banting, W R Campbell, C H Best, A A Fletcher, J B Collip, Pancreatic Extracts in the Treatment of Diabetes Mellitus. Canadian Medical Association Journal. ,vol. 12, pp. 141- 146 ,(1922)
J Meyerovitch, Z Farfel, J Sack, Y Shechter, Oral administration of vanadate normalizes blood glucose levels in streptozotocin-treated rats. Characterization and mode of action. Journal of Biological Chemistry. ,vol. 262, pp. 6658- 6662 ,(1987) , 10.1016/S0021-9258(18)48292-0
J Gil, M Miralpeix, J Carreras, R Bartrons, Insulin-like effects of vanadate on glucokinase activity and fructose 2,6-bisphosphate levels in the liver of diabetic rats. Journal of Biological Chemistry. ,vol. 263, pp. 1868- 1871 ,(1988) , 10.1016/S0021-9258(19)77957-5
A Green, The insulin-like effect of sodium vanadate on adipocyte glucose transport is mediated at a post-insulin-receptor level. Biochemical Journal. ,vol. 238, pp. 663- 669 ,(1986) , 10.1042/BJ2380663
J Meyerovitch, P Rothenberg, Y Shechter, S Bonner-Weir, C R Kahn, Vanadate normalizes hyperglycemia in two mouse models of non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation. ,vol. 87, pp. 1286- 1294 ,(1991) , 10.1172/JCI115131
Hadassa Degani, Miriam Gochin, Steven J. D. Karlish, Yoram Shechter, Electron paramagnetic resonance studies and insulin-like effects of vanadium in rat adipocytes. Biochemistry. ,vol. 20, pp. 5795- 5799 ,(1981) , 10.1021/BI00523A023
T. J. B. Simons, Vanadate--a new tool for biologists. Nature. ,vol. 281, pp. 337- 338 ,(1979) , 10.1038/281337A0
S. Ramanadham, G. H. Cros, J. J. Mongold, J. J. Serrano, J. H. McNeill, Enhanced in vivo sensitivity of vanadyl-treated diabetic rats to insulin. Canadian Journal of Physiology and Pharmacology. ,vol. 68, pp. 486- 491 ,(1990) , 10.1139/Y90-069
W. Timothy Garvey, Insulin resistance and noninsulin-dependent diabetes mellitus: which horse is pulling the cart? Diabetes \/ Metabolism Reviews. ,vol. 5, pp. 727- 742 ,(1989) , 10.1002/DMR.5610050807
S. M. Brichard, C. J. Bailey, J.-C. Henquin, Marked improvement of glucose homeostasis in diabetic ob/ob mice given oral vanadate. Diabetes. ,vol. 39, pp. 1326- 1332 ,(1990) , 10.2337/DIAB.39.11.1326