Association of Transferable Quinolone Resistance Determinant qnrB19 with Extended-Spectrum β-Lactamases in Salmonella Give and Salmonella Heidelberg in Venezuela
作者： Fanny González , María Araque
DOI: 10.1155/2013/628185
关键词:
摘要: Four nontyphoidal Salmonella strains with resistance to extended-spectrum cephalosporins and nonclassical quinolone phenotype were studied. Two S. Give isolated from pediatric patients acute gastroenteritis, two Heidelberg recovered raw chicken meat. Phenotypic characterization included antimicrobial susceptibility testing detection of β-lactamases (ESBLs) by the double-disc synergy method. The resistance-determining regions (QRDR) gyrA, gyrB, gyrC genes, plasmid-mediated (PMQR) determinants was carried out molecular methods. Plasmid analysis Southern blot restriction patterns. Transferability genes examined transformation. detected in SG9611 other three strains: SG9811, SH7511, SH7911. Regardless origin serovars, qnrB19 gene 4 All localized plasmids successfully transferred This study highlights circulation associated , Venezuela. recognition factors increasing mechanisms involved can lead a more focused use agents.
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