Cell surface proteins and malignant transformation.

作者: R Hynes

DOI: 10.1016/0304-419X(76)90015-9

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摘要: Abstract Many of the altered properties malignant cells are thought to involve alterations in cell surface functions. In order understand these it is necessary know more about molecular structure surface. Methods for analyzing proteins discussed and their application normal transformed tissue culture reviewed. A number observed be by transformation. Most reductions amounts particular species, although a few do increase. Evidence concerning reasons possible functions some molecules Working hypotheses arising from data presented prospects understanding physiological changes terms effects discussed. Particular emphasis placed on idea that associated specific-non-covalent complexes which important

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