Small lung tumors with the size of 1cm or less in diameter: clinical, radiological, and histopathological characteristics

作者: Kazuma Kishi , Sakae Homma , Atsuko Kurosaki , Noriko Motoi , Tadasu Kohno

DOI: 10.1016/J.LUNGCAN.2003.09.024

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摘要: Abstract Background: The detection rate of small nodules in the peripheral lung area is increasing due to widespread use CT scanning. However, radiological and pathological characteristics very tumors have not been fully investigated. Methods: We evaluated 44 with size 1 cm or less diameter resected from 38 patients (19 men 19 women, an average 62 years) 1997 through 2001. clinical records, findings high-resolution (HRCT) histopathological features specimens were analyzed. Adenocarcinoma was histologically further subclassified into types A F according Noguchi’s classification. Results: Lobectomy performed 20 patients, wedge resection 15 segmentectomy 3, respectively. Thirty-two adenocarcinomas, 4 squamous cell carcinomas, eight atypical adenomatous hyperplasia (AAH), All carcinoma cases proved be stage IA. In adenocarcinoma, type detected 12 tumors, B 13, C 1, D 2, E Most AAH showed pure ground-glass attenuation on HRCT scan, whereas as well frequently had malignant signs such lobulation convergence vessels. Lymphatic vascular invasion observed two adenocarcinomas (types F) scan these four soft-tissue occupying more than two-thirds each nodule. are currently alive without recurrence after a mean follow-up period 35.5 months. Conclusion: Types adenocarcinoma most common histologic among diameter. Limited appears adequate for which consists nodule HRCT.

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