A Molecular Approach to Mitophagy and Mitochondrial Dynamics.
作者： Seung-Min Yoo , Yong-Keun Jung
DOI: 10.14348/MOLCELLS.2018.2277
关键词:
摘要: Mitochondrial quality control systems are essential for the maintenance of functional mitochondria. At organelle level, they include mitochondrial biogenesis, fusion and fission, to compensate function, mitophagy, degrading damaged Specifically, in target mitochondria recognized by autophagosomes delivered lysosome degradation. In this review, we describe mechanisms mitophagy factors that play an important role process. particular, focus on roles adapters receptors recognition autophagosomes. addition, also address a association with dynamics through interaction adaptor receptor proteins fission proteins.
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