Human epidermal growth factor receptor-2 family in colorectal adenocarcinoma: Correlation with survival and clinicopathological findings

作者: Mahsa Molaei , Shervin Pejhan , Babak Noori Nayer , Afshin Moradi , Somaye Ghiasi

DOI: 10.1097/MEG.0B013E32830B82BA

关键词:

摘要: Background and PurposeErb-B1 (epidermal growth factor receptor, EGFR) Erb-B2 (HER-2) are two of the best-characterized members in EGFR pathway. In many tumor types, overexpression these proteins is associated with enhanced malignant potential. The aim this study was to determine pr

参考文章(43)
Harlan W. Waksal, Role of an anti-epidermal growth factor receptor in treating cancer. Cancer and Metastasis Reviews. ,vol. 18, pp. 427- 436 ,(1999) , 10.1023/A:1006302101468
William F. Anderson, Asad Umar, Otis W. Brawley, Colorectal carcinoma in black and white race. Cancer and Metastasis Reviews. ,vol. 22, pp. 67- 82 ,(2003) , 10.1023/A:1022264002228
S Toikkanen, H Helin, J Isola, H Joensuu, Prognostic significance of HER-2 oncoprotein expression in breast cancer: a 30-year follow-up. Journal of Clinical Oncology. ,vol. 10, pp. 1044- 1048 ,(1992) , 10.1200/JCO.1992.10.7.1044
Furuzan Kacar Doger, Ibrahim Meteoglu, Pars Tuncyurek, Pinar Okyay, Hakan Cevikel, Does the EGFR and VEGF expression predict the prognosis in colon cancer European Surgical Research. ,vol. 38, pp. 540- 544 ,(2006) , 10.1159/000096774
Sharadah Essapen, Hilary Thomas, Margaret Green, Corrine De Vries, Martin Cook, Christopher Marks, Clare Topham, Helmout Modjtahedi, The expression and prognostic significance of HER-2 in colorectal cancer and its relationship with clinicopathological parameters International Journal of Oncology. ,vol. 24, pp. 241- 248 ,(2004) , 10.3892/IJO.24.2.241
Karin Koretz, Peter Schlag, Peter Möller, Expression of epidermal growth factor receptor in normal colorectal mucosa, adenoma, and carcinoma. Virchows Archiv. ,vol. 416, pp. 343- 349 ,(1990) , 10.1007/BF01605295
A.M. Kluftinger, B.W. Robinson, N.F. Quenville, R.J. Finley, N.L. Davis, Correlation of epidermal growth factor receptor and c-erbB2 oncogene product to known prognostic indicators of colorectal cancer. Surgical Oncology-oxford. ,vol. 1, pp. 97- 105 ,(1992) , 10.1016/0960-7404(92)90062-P
J. L. Formento, M. Francoual, P. Formento, M. C. Etienne, J. L. Fischel, M. Namer, M. Frenay, E. François, G. Milano, Epidermal growth factor receptor assay: Validation of a single point method and application to breast cancer Breast Cancer Research and Treatment. ,vol. 17, pp. 211- 219 ,(1991) , 10.1007/BF01806370
A H Arnaout, P M Dawson, S Soomro, P Taylor, N A Theodorou, M Feldmann, B M Fendly, H M Shepard, S Shousha, HER2 (c-erbB-2) oncoprotein expression in colorectal adenocarcinoma: an immunohistological study using three different antibodies. Journal of Clinical Pathology. ,vol. 45, pp. 726- 727 ,(1992) , 10.1136/JCP.45.8.726
Elizabeth Half, Russell Broaddus, Kathleen D. Danenberg, Peter V. Danenberg, Gregory D. Ayers, Frank A. Sinicrope, HER-2 receptor expression, localization, and activation in colorectal cancer cell lines and human tumors International Journal of Cancer. ,vol. 108, pp. 540- 548 ,(2004) , 10.1002/IJC.11599