Adenoid cystic carcinoma of the airway: a 30-year review at one institution

摘要: Abstract Purpose The purpose of the study was to evaluate treatment results adenoid cystic carcinoma (ACC) airway at a single institution during 30-year period. Materials and methods All cases ACC over period one tertiary care were reviewed retrospectively. demographics, modalities, pathologic characteristics, outcomes evaluated. Results Eleven patients treated for with an age range 25 72 years (median, 48 years). Six presented in larynx, 5 had trachea. underwent surgical excision radiation; 9 11 postoperative external beam radiation, 1 patient preoperative remaining neutron therapy. Four tracheal none laryngeal microscopic or grossly positive margins after surgery ( P = .048). Eighty percent perineural invasion on pathology. Two local recurrence disease, which occurred 10 months postoperatively. One died distant metastatic disease 16 months. Follow-up varied from 4 168 31 months). Conclusions We report high disease-free survival rates who definitive resection followed by radiation. There is higher risk distal location. Distant ultimately determines survival.