A simple method of detecting K-ras point mutations in stool samples for colorectal cancer screening using one-step polymerase chain reaction/restriction fragment length polymorphism analysis.
作者： Hiroshi Morikawa , Ken Toshina , Mitsuyuki Murano , Keiichi Hashimoto , Yoshihito Nakagawa
DOI: 10.1016/S0009-8981(01)00806-3
关键词:
摘要: … Results: The K-ras gene was successfully amplified from all healthy controls and colorectal cancer patients studied. Mutations of K-ras codon 12 were not detected in any of the healthy …
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