Isolation and identification of antibacterial neo-compounds from the red ants of ChangBai Mountain, Tetramorium sp.

作者: Zheng-Wei Song , Pu Liu , Wei-Ping Yin , Ya-Ling Jiang , Yun-lai Ren

DOI: 10.1016/J.BMCL.2012.01.112

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摘要: Abstract Three novel coumarin compounds along with two known amide alkaloids were isolated from a methanol extract of the red ants ChangBai Mountain, Tetramorium sp . Their structures identified on basis IR, 2D NMR ( 1 H– H COSY, HSQC, HMBC and NOESY) HRESIMS analysis. Antibacterial activity all was evaluated using KB paper diffusion through measurement inhibiting zone. It found that four exhibited significant inhibitory against Gram-positive bacteria Bacillus subtilis MIC values 25 μg/ml (compounds – 3 ) 15 μg/ml (compound 4 ).

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