Transplacental stimulation of functional and morphologic fetal rabbit lung maturation: Effect of thyrotropin-releasing hormone

作者: Uday Devaskar , Kenneth Nitta , Karl Szewczyk , H. Farouk Sadiq , Daphne deMello

DOI: 10.1016/S0002-9378(87)80195-3

关键词:

摘要: We investigated the effect of maternally administered thyrotropin-releasing hormone on functional and morphologic fetal lung maturation. Thyrotropin-releasing (40 μg/kg/day) or vehicle was injected intravenously into New Zealand White rabbit does days 25, 26, 27 gestation. On day pregnancy, were killed fetuses delivered. The pulmonary maturity assessed by pressure-volume hysteresis while histologic techniques. Enhanced maturation noted in animals treated with when compared controls. An important role is proposed.

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