Evaluation of recurrent squamous cell carcinoma of the head and neck with FDG positron emission tomography.

摘要: Purpose: This study compared the effectiveness of fluorodeoxyglucose (FDG) positron emission tomography (PET) with computed (CT), magnetic resonance imaging (MRI), or both for assessment recurrent squamous cell carcinoma head and neck. The value quantifying standardized uptake values (SUV) to distinguish neoplasm from inflammatory lesions normal structures was also evaluated. Methods: Forty-three patients neck cancer were examined F-18 FDG PET at least 4 months after their last course radiation therapy (mean, 11 months). SUVs measured in visually identified regions abnormally increased activity mucosa, base tongue, hard palate determine if an optimal cutoff exists diagnosing recurrence malignant lesions. final diagnosis made based on biopsy 6 months' clinical follow-up. Results: correctly detected 20 22 who had 45 discrete located field upper aerodigestive tract. Two false-negative three false-positive results identified. accuracy 88% (38 43 patients), 66% (25 38 patients) CT, MRI, both. Although there a significant difference (P = 0.0036) between structures, difficult define. Conclusions: Visual analysis is significantly more accurate than are CT MRI. However, single SUV quantification does not enhance efficacy.