Inhibition of melanogenesis as an adjuvant strategy in the treatment of melanotic melanomas : Selective review and hypothesis
作者： ANDRzEI Slominski , RALF PAUs , MC Mihm
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摘要: Melanogenesis generates immunosuppressive and mutagenic environment alters cellular metabolism. Melanin can protect malignant melanocytes against chemo-, radio-, photodynamic therapy. Therefore, we propose to inhibit melanogenesis as an adjuvant treatment modality during immuno-, chemo- therapy, a measure of reducing the probability melanoma progression.
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