The Introduction of Systematic Genomic Testing for Patients With Non-Small-Cell Lung Cancer

作者: Stephanie Cardarella , Taylor M. Ortiz , Victoria A. Joshi , Mohit Butaney , David M. Jackman

DOI: 10.1097/JTO.0B013E3182745BCB

关键词: GenotypingLung cancerInternal medicineMedicineCancerCarcinomaKRASFluorescence in situ hybridizationPersonalized medicineTargeted therapyOncology

摘要: … Large-scale testing for somatic alterations in EGFR, KRAS, BRAF, PIK3CA, HER2, and … 4-micron sections of FFPE tumor samples cut onto glass slides, using an ALK break-apart probe (…

参考文章(29)
Robert Pirker, Felix JF Herth, Keith M Kerr, Martin Filipits, Miquel Taron, David Gandara, Fred R Hirsch, Dominique Grunenwald, Helmut Popper, Egbert Smit, Manfred Dietel, Antonio Marchetti, Christian Manegold, Peter Schirmacher, Michael Thomas, Rafael Rosell, Federico Cappuzzo, Rolf Stahel, European EGFR Workshop Group, None, Consensus for EGFR Mutation Testing in Non-small Cell Lung Cancer: Results from a European Workshop Journal of Thoracic Oncology. ,vol. 5, pp. 1706- 1713 ,(2010) , 10.1097/JTO.0B013E3181F1C8DE
Chenguang Li, Rong Fang, Yihua Sun, Xiangkun Han, Fei Li, Bin Gao, A. John Iafrate, Xin-Yuan Liu, William Pao, Haiquan Chen, Hongbin Ji, Spectrum of Oncogenic Driver Mutations in Lung Adenocarcinomas from East Asian Never Smokers PLoS ONE. ,vol. 6, pp. e28204- ,(2011) , 10.1371/JOURNAL.PONE.0028204
J. A. Engelman, K. Zejnullahu, T. Mitsudomi, Y. Song, C. Hyland, J. O. Park, N. Lindeman, C.-M. Gale, X. Zhao, J. Christensen, T. Kosaka, A. J. Holmes, A. M. Rogers, F. Cappuzzo, T. Mok, C. Lee, B. E. Johnson, L. C. Cantley, P. A. Janne, MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling Science. ,vol. 316, pp. 1039- 1043 ,(2007) , 10.1126/SCIENCE.1141478
Takashi Kubo, Yukie Kuroda, Akiko Kokubu, Fumie Hosoda, Yasuhito Arai, Nobuyoshi Hiraoka, Setsuo Hirohashi, Tatsuhiro Shibata, Resequencing Analysis of the Human Tyrosine Kinase Gene Family in Pancreatic Cancer Pancreas. ,vol. 38, pp. e200- e206 ,(2009) , 10.1097/MPA.0B013E3181B8FEB0
Doron Lipson, Marzia Capelletti, Roman Yelensky, Geoff Otto, Alex Parker, Mirna Jarosz, John A Curran, Sohail Balasubramanian, Troy Bloom, Kristina W Brennan, Amy Donahue, Sean R Downing, Garrett M Frampton, Lazaro Garcia, Frank Juhn, Kathy C Mitchell, Emily White, Jared White, Zac Zwirko, Tamar Peretz, Hovav Nechushtan, Lior Soussan-Gutman, Jhingook Kim, Hidefumi Sasaki, Hyeong Ryul Kim, Seung-il Park, Dalia Ercan, Christine E Sheehan, Jeffrey S Ross, Maureen T Cronin, Pasi A Jänne, Philip J Stephens, Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies Nature Medicine. ,vol. 18, pp. 382- 384 ,(2012) , 10.1038/NM.2673
Joan H. Schiller, David Harrington, Chandra P. Belani, Corey Langer, Alan Sandler, James Krook, Junming Zhu, David H. Johnson, Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. The New England Journal of Medicine. ,vol. 346, pp. 92- 98 ,(2002) , 10.1056/NEJMOA011954
Gulcan Baloglu, Aptullah Haholu, Zafer Kucukodaci, Ismail Yilmaz, Sukru Yildirim, Huseyin Baloglu, The Effects of Tissue Fixation Alternatives on DNA Content Applied Immunohistochemistry & Molecular Morphology. ,vol. 16, pp. 485- 492 ,(2008) , 10.1097/PAI.0B013E31815DFFA6
Giorgio Vittorio Scagliotti, Purvish Parikh, Joachim von Pawel, Bonne Biesma, Johan Vansteenkiste, Christian Manegold, Piotr Serwatowski, Ulrich Gatzemeier, Raghunadharao Digumarti, Mauro Zukin, Jin S. Lee, Anders Mellemgaard, Keunchil Park, Shehkar Patil, Janusz Rolski, Tuncay Goksel, Filippo de Marinis, Lorinda Simms, Katherine P. Sugarman, David Gandara, Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer Journal of Clinical Oncology. ,vol. 26, pp. 3543- 3551 ,(2008) , 10.1200/JCO.2007.15.0375
Dora Dias‐Santagata, Sara Akhavanfard, Serena S. David, Kathy Vernovsky, Georgiana Kuhlmann, Susan L. Boisvert, Hannah Stubbs, Ultan McDermott, Jeffrey Settleman, Eunice L. Kwak, Jeffrey W. Clark, Steven J. Isakoff, Lecia V. Sequist, Jeffrey A. Engelman, Thomas J. Lynch, Daniel A. Haber, David N. Louis, Leif W. Ellisen, Darrell R. Borger, A. John Iafrate, Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine Embo Molecular Medicine. ,vol. 2, pp. 146- 158 ,(2010) , 10.1002/EMMM.201000070
Eunice L. Kwak, Yung-Jue Bang, D. Ross Camidge, Alice T. Shaw, Benjamin Solomon, Robert G. Maki, Sai-Hong I. Ou, Bruce J. Dezube, Pasi A. Jänne, Daniel B. Costa, Marileila Varella-Garcia, Woo-Ho Kim, Thomas J. Lynch, Panos Fidias, Hannah Stubbs, Jeffrey A. Engelman, Lecia V. Sequist, WeiWei Tan, Leena Gandhi, Mari Mino-Kenudson, Greg C. Wei, S. Martin Shreeve, Mark J. Ratain, Jeffrey Settleman, James G. Christensen, Daniel A. Haber, Keith Wilner, Ravi Salgia, Geoffrey I. Shapiro, Jeffrey W. Clark, A. John Iafrate, Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer The New England Journal of Medicine. ,vol. 363, pp. 1693- 1703 ,(2010) , 10.1056/NEJMOA1006448