SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma

作者: Myung Jin Son , Kevin Woolard , Do-Hyun Nam , Jeongwu Lee , Howard A. Fine

DOI: 10.1016/J.STEM.2009.03.003

关键词: GlioblastomaCancer researchFlow cytometryCellular differentiationCell growthCell cycleImmunologyCancerBiologyTumor cellsTumor Initiating Cells

摘要: … we did not find SSEA-1+ staining was the tumor from which the only SSEA-1− TSC/TIC line … of antibody staining and the consistency of SSEA-1 status in early passage cells and the …

参考文章(54)
Sheri Miraglia, Wayne Godfrey, Amy H. Yin, Kristin Atkins, Roger Warnke, Jeannine T. Holden, Robert A. Bray, Edmund K. Waller, David W. Buck, A novel five-transmembrane hematopoietic stem cell antigen: isolation, characterization, and molecular cloning. Blood. ,vol. 90, pp. 5013- 5021 ,(1997) , 10.1182/BLOOD.V90.12.5013
Paul Kleihues, David N. Louis, Bernd W. Scheithauer, Lucy B. Rorke, Guido Reifenberger, Peter C. Burger, Webster K. Cavenee, The WHO Classification of Tumors of the Nervous System Journal of Neuropathology and Experimental Neurology. ,vol. 61, pp. 215- 225 ,(2002) , 10.1093/JNEN/61.3.215
Corinne E. Griguer, Claudia R. Oliva, Eric Gobin, Pascale Marcorelles, Dale J. Benos, Jack R. Lancaster, G. Yancey Gillespie, CD133 Is a Marker of Bioenergetic Stress in Human Glioma PLoS ONE. ,vol. 3, pp. e3655- 289 ,(2008) , 10.1371/JOURNAL.PONE.0003655
Jeongwu Lee, Myung Jin Son, Kevin Woolard, Nicholas M. Donin, Aiguo Li, Chui H. Cheng, Svetlana Kotliarova, Yuri Kotliarov, Jennifer Walling, Susie Ahn, Misuk Kim, Mariam Totonchy, Thomas Cusack, Chibawanye Ene, Hilary Ma, Qin Su, Jean Claude Zenklusen, Wei Zhang, Dragan Maric, Howard A. Fine, Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells. Cancer Cell. ,vol. 13, pp. 69- 80 ,(2008) , 10.1016/J.CCR.2007.12.005
Urban Lendahl, Lyle B. Zimmerman, Ronald D.G. McKay, CNS stem cells express a new class of intermediate filament protein. Cell. ,vol. 60, pp. 585- 595 ,(1990) , 10.1016/0092-8674(90)90662-X
Dagmar Beier, Peter Hau, Martin Proescholdt, Annette Lohmeier, Jörg Wischhusen, Peter J. Oefner, Ludwig Aigner, Alexander Brawanski, Ulrich Bogdahn, Christoph P. Beier, CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Research. ,vol. 67, pp. 4010- 4015 ,(2007) , 10.1158/0008-5472.CAN-06-4180
Michael F Clarke, John E Dick, Peter B Dirks, Connie J Eaves, Catriona HM Jamieson, D Leanne Jones, Jane Visvader, Irving L Weissman, Geoffrey M Wahl, None, Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Research. ,vol. 66, pp. 9339- 9344 ,(2006) , 10.1158/0008-5472.CAN-06-3126
Angelo L. Vescovi, Rossella Galli, Brent A. Reynolds, Brain tumour stem cells Nature Reviews Cancer. ,vol. 6, pp. 425- 436 ,(2006) , 10.1038/NRC1889
V. Coskun, H. Wu, B. Blanchi, S. Tsao, K. Kim, J. Zhao, J. C. Biancotti, L. Hutnick, R. C. Krueger, G. Fan, J. de Vellis, Y. E. Sun, CD133+ neural stem cells in the ependyma of mammalian postnatal forebrain Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 1026- 1031 ,(2008) , 10.1073/PNAS.0710000105