Molecular Targeting and Treatment of an Epidermal Growth Factor Receptor–Positive Glioma Using Boronated Cetuximab

作者: G. Wu , W. Yang , R. F. Barth , S. Kawabata , M. Swindall

DOI: 10.1158/1078-0432.CCR-06-2399

关键词: Growth factorSodium BorocaptateCetuximabIn vitroCancer researchEpidermal growth factor receptorGrowth factor receptorImmunologyGliomaMonoclonal antibodyChemistry

摘要: Purpose: The purpose of the present study was to evaluate the anti–epidermal growth factor monoclonal antibody (mAb) cetuximab (IMC-C225) as a delivery agent for boron neutron …

参考文章(60)
Jorge L Eller, Sharon L Longo, Michele M Kyle, Daniel Bassano, Daniel J Hicklin, Gregory W Canute, None, Anti-epidermal growth factor receptor monoclonal antibody cetuximab augments radiation effects in glioblastoma multiforme in vitro and in vivo. Neurosurgery. ,vol. 56, pp. 155- 162 ,(2005) , 10.1227/01.NEU.0000145865.25689.55
G. H. Sato, J. Mendelsohn, J. Polikoff, J. D. Sato, A. D. Le, T. Kawamoto, Biological effects in vitro of monoclonal antibodies to human epidermal growth factor receptors. Molecular biology & medicine. ,vol. 1, pp. 511- 529 ,(1983)
Burt G. Feuerstein, Frederic M. Waldman, Richard L. Davis, Guido Sauter, Tatsuhiro Maeda, Patterns of epidermal growth factor receptor amplification in malignant gliomas. American Journal of Pathology. ,vol. 148, pp. 1047- 1053 ,(1996)
Advances in neutron capture therapy Plenum Press,New York (United States). ,(1993) , 10.1007/978-1-4615-2978-1
Werner Tjarks, Robert A Fenstermaker, Michael A Caligiuri, Supriya Shukla, Michael J Ciesielski, Rolf F Barth, Weilian Yang, Dianne M Adams, Convection-enhanced delivery of boronated epidermal growth factor for molecular targeting of EGF receptor-positive gliomas. Cancer Research. ,vol. 62, pp. 6552- 6558 ,(2002)
Bea Pauwels, Annelies E. C. Korst, Christel M. J. de Pooter, Greet G. O. Pattyn, Hilde A. J. Lambrechts, Marc F. D. Baay, Filip Lardon, Jan B. Vermorken, Comparison of the sulforhodamine B assay and the clonogenic assay for in vitro chemoradiation studies. Cancer Chemotherapy and Pharmacology. ,vol. 51, pp. 221- 226 ,(2003) , 10.1007/S00280-002-0557-9
Werner Tjarks, Robert A Fenstermaker, Joan H Rotaru, Marta M Nawrocky, Jeffrey A Coderre, Supriya Shukla, Michael Ciesielski, Rolf F Barth, Weilian Yang, Dianne M Adams, Masaru Sekido, Molecular targeting of the epidermal growth factor receptor for neutron capture therapy of gliomas. Cancer Research. ,vol. 62, pp. 3159- 3166 ,(2002)
Paul Perrotte, Hiroki Kuniyasu, Beryl Y. Eve, Daniel J. Hicklin, Keiji Inoue, Colin P. N. Dinney, Robert Radinsky, Takashi Matsumoto, Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice. Clinical Cancer Research. ,vol. 5, pp. 257- 265 ,(1999)