Epidermal growth factor receptor gene and immunohistochemical expression in colorectal carcinomas
作者： Torill Sauer
DOI: 10.1016/J.MPDHP.2007.12.005
关键词: Immunohistochemistry 、 Colorectal cancer 、 Epidermal growth factor receptor 、 In situ hybridization 、 Gene 、 Normal colon 、 Biology 、 Monoclonal antibody therapy 、 Pathology 、 Histopathology
摘要: Abstract Expression of epidermal growth factor receptor (EGFR) protein can be found in normal colon mucosa, adenomas, and carcinomas. Its impact on prognosis colorectal carcinomas is moderate, but the availability a monoclonal antibody therapy designed to block EGFR has brought it into prominence diagnostic histopathology. The literature reports wide variance expression primary tumours metastases, ranging from
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