Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition
作者： A. C. Faber , D. Li , Y. Song , M.-C. Liang , B. Y. Yeap
关键词: PI3K/AKT/mTOR pathway 、 Protein kinase B 、 Erlotinib 、 Cancer research 、 Epidermal growth factor receptor 、 Signal transduction 、 Biology 、 Erlotinib Hydrochloride 、 Gefitinib 、 Apoptosis
摘要: Non-small cell lung cancers with activating mutations in the epidermal growth factor receptor (EGFR) are highly responsive to EGFR tyrosine kinase inhibitors (TKIs), such as gefitinib …
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