How many mutations does it take to make a tumor
作者： C. R. Boland , L. Ricciardiello
关键词: Mutation 、 Front page 、 Cancer 、 Context (language use) 、 Genome instability 、 Bioinformatics 、 Adenomatous polyps 、 Biology
摘要: In this issue of PNAS, Stoler and col-leagues report that typical sporadic colorectal cancers on average contain at least 11,000 genomic alterations per cell (1). Furthermore, they report …
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