Medium Optimization of Gamma Linolenic Acid Production in Mucor rouxii CFR -G15 using RSM
作者： S. S. Mamatha , R. Ravi , G. Venkateswaran
DOI: 10.1007/S11947-008-0103-9
关键词: Polyunsaturated fatty acid 、 Fermentation 、 Ammonium nitrate 、 Yeast extract 、 Response surface methodology 、 Biochemistry 、 gamma-Linolenic acid 、 Food science 、 Nitrogen 、 Mucor rouxii 、 Biology
摘要: Omega-6 polyunsaturated fatty acids has both pharmaceutical and neutraceutical importance. Central composite rotatable design (CCRD), along with response surface methodology (RSM), was employed to optimize the medium components for maximum production of gamma linolenic acid (GLA) from Mucor rouxii CFR-G15. Nutritional parameter such as carbon (glucose) nitrogen (yeast extract ammonium nitrate) sources were focused in this study enhance GLA production. The optimal conditions maximizing (18.55%) at 65 g glucose per liter; 3.5 yeast liter, 0.5 nitrate liter. Thus, by using CCRD RSM, it is quite possible determine accurate values fermentation parameters where achieved.
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