Identification and characterization of a Drosophila homologue of ATBP.
作者： N. Aozasa , Takeo Kubo , Kazuhisa Sekimizu , Shunji Natori
DOI: 10.1046/J.0962-1075.2001.00304.X
关键词: Promoter 、 Peptide sequence 、 Gene 、 Drosophila melanogaster 、 Transcription factor 、 Molecular biology 、 Binding protein 、 Biology 、 Sarcophaga 、 Luciferase
摘要: ATBP [(A+T)-stretch binding protein] activates the Sarcophaga defense protein genes in an (A+T)-stretch dependent manner as shown previously using a luciferase reporter assay [Aozasa et al. (2001) Eur J Biochem, 268, 2506-2511]. We identified Drosophila homologue of ATBP. has 388 amino acid residues and sequence high similarity with that In particular, 1-56 301-374 are highly conserved between Drosophila. activated lectin gene promoter SL-2 cells. The is single copy located 20E region chromosome X.
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