作者: Heinz-Josef Lenz
DOI:
关键词: Gene 、 Bioinformatics 、 Antibody 、 Biology 、 Genotype 、 Combination therapy 、 Pharmacology 、 Topoisomerase inhibitor 、 Genetic marker
摘要: The invention provides compositions and methods for determining the likelihood of successful treatment with an effective amount anti-VEGF antibody or equivalent thereof, in combination anti-EGFR and, some aspects a topoisomerase inhibitor. comprise identity gene interest patient sample correlating patient's genotype predictive response. Patients identified as responsive are then treated appropriate therapy.