Taxane-induced apoptosis decompresses blood vessels and lowers interstitial fluid pressure in solid tumors: clinical implications.
作者： Herman D. Suit , Genevièeve Griffon-Etienne , Christian Brekken , Yves Boucher , Rakesh K. Jain
DOI:
关键词: Vascular resistance 、 Paclitaxel 、 Interstitial fluid 、 Sarcoma 、 Taxane 、 Biology 、 Blood vessel 、 Neoplastic cell 、 Pathology 、 Docetaxel
摘要: … tumor interstitial fluid pressure (IFP) is partly responsible for the poor penetration and distribution of therapeutic agents in solid tumors… changes in pressure with tumor growth, the IFPs of …
aacrjournals.org参考文章(33)
A. R. Perez-Atayde, S. E. Sallan, U. Tedrow, J. Folkman, S. Connors, E. Allred, Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. American Journal of Pathology. ,vol. 150, pp. 815- 821 ,(1997)
Alwin E. Goetz, Fan Yuan, Yves Boucher, Rakesh K. Jain, Konrad Messmer, Michael Leunig, Michael D. Menger, Angiogenesis, Microvascular Architecture, Microhemodynamics, and Interstitial Fluid Pressure during Early Growth of Human Adenocarcinoma LS174T in SCID Mice Cancer Research. ,vol. 52, pp. 6553- 6560 ,(1992)
Laurence T. Baxter, Rakesh K. Jain, Transport of fluid and macromolecules in tumors. III. Role of binding and metabolism. Microvascular Research. ,vol. 41, pp. 5- 23 ,(1991) , 10.1016/0026-2862(91)90003-T
James Wei, Pietro M. Gullino, Edward A. Swabb, Diffusion and Convection in Normal and Neoplastic Tissues Cancer Research. ,vol. 34, pp. 2814- 2822 ,(1974)
Yves Boucher, Rakesh K. Jain, Microvascular Pressure Is the Principal Driving Force for Interstitial Hypertension in Solid Tumors: Implications for Vascular Collapse Cancer Research. ,vol. 52, pp. 5110- 5114 ,(1992)
Luka Milas, Nancy R. Hunter, Kathryn A. Mason, Yoshihiro Saito, Lester J. Peters, Christopher G. Milross, Role of Reoxygenation in Induction of Enhancement of Tumor Radioresponse by Paclitaxel Cancer Research. ,vol. 55, pp. 3564- 3568 ,(1995)
Yves Boucher, Rakesh K. Jain, Michael Leunig, Tumor Angiogenesis and Interstitial Hypertension Cancer Research. ,vol. 56, pp. 4264- 4266 ,(1996)
Françoise Guéritte-Voegelein, François Lavelle, Daniel Guénard, Marie-Christine Bissery, Experimental Antitumor Activity of Taxotere (RP 56976, NSC 628503), a Taxol Analogue Cancer Research. ,vol. 51, pp. 4845- 4852 ,(1991)
Joan Albanell, Larry Norton, Jose Baselga, Young Mee Kim, John Mendelsohn, Recombinant Humanized anti-HER2 Antibody (Herceptin) Enhances the Antitumor Activity of Paclitaxel and Doxorubicin Against HER2/neu Overexpressing Human Breast Cancer Xenografts Cancer Research. ,vol. 58, pp. 2825- 2831 ,(1998)
Paolo A. Netti, Sylvie Roberge, Yves Boucher, Laurence T. Baxter, Rakesh K. Jain, Effect of transvascular fluid exchange on pressure-flow relationship in tumors: a proposed mechanism for tumor blood flow heterogeneity. Microvascular Research. ,vol. 52, pp. 27- 46 ,(1996) , 10.1006/MVRE.1996.0041