Phenomenological approaches to collective behavior in epithelial cell migration.

摘要: Collective cell migration in epithelial tissues resembles fluid-like behavior time-lapse recordings. In the last years, hydrodynamic velocity fields living matter have been studied intensely. The emergent properties were remarkably similar to phenomena known from active soft systems. Here, we review experiments of large cellular ensembles as well mesoscopic cohorts micro-structured environments. Concepts such diffusion, correlations, swirl strength and polarization are metrics quantify dynamics both computational simulations. We discuss challenges relating collective single oligocellular linking phenotypic parameters underlying cytoskeleton signaling networks. This article is part a Special Issue entitled: Mechanobiology.