LigAmp for sensitive detection of single-nucleotide differences

作者: Chanjuan Shi , Susan H Eshleman , Dana Jones , Noriyoshi Fukushima , Li Hua

DOI: 10.1038/NMETH713

关键词: DNAA-DNANucleotidePlasmidBiologyMolecular biologyPancreatic cancerOligonucleotideMutationMutant

摘要: … We report here a simple, universal strategy for sensitive detection and quantification of … : (i) detection of KRAS2 and TP53 mutations for early detection of cancer and (ii) detection of the …

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