Phocine herpesvirus 1 (PhHV-1) in harbor seals from Svalbard, Norway.

摘要: Phocine herpesvirus 1 (PhHV-1) infections in seals are associated with disease and sometimes high mortality, primarily young animals. PhHV-1 has been detected from European waters as well on both coasts of North America. Serological surveys various pinniped species have indicated a wide geographical distribution PhHV-1. A quantitative sensitive real-time PCR assay targeting the gene encoding glycoprotein B was developed for detection ocular nasal swab samples wild harbor (Phoca vitulina) Svalbard (Norway). DNA 6 (8%) collected 2009 2 (3%) 2010; all had sample, whereas only one these animals also sample. Four positive were approximately year age four pups year. Serum obtained 1998 (n=59), 1999 (n=74), 2000 (n=81), (n=69) 2010 (n=83) tested anti-PhHV-1 antibodies an indirect ELISA. The seroprevalence population remained throughout this period, varying 77 to 100% between years. No eye observed seal population, but ELISA findings reported here suggest that is endemic globally northernmost colony, virus shed mucosa nose.