Molecular Mechanisms Underlying Effects of Epidermal Growth Factor Receptor Inhibition on Invasion, Proliferation, and Angiogenesis in Experimental Glioma
作者： Jean-Sébastien Guillamo , Sophie de Boüard , Samuel Valable , Lena Marteau , Pascal Leuraud
DOI: 10.1158/1078-0432.CCR-08-2042
关键词: Metastasis 、 Cancer research 、 PTEN 、 Protein kinase B 、 Growth factor receptor 、 Epidermal growth factor receptor 、 Angiogenesis 、 Gefitinib 、 Pathology 、 Glioma 、 Biology 、 Oncology
摘要: Purpose: Epidermal growth factor receptor (EGFR) signal transduction pathways are implicated in malignant glioma aggressiveness and promote tumor cell invasion, proliferation, and …
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