Diet During Pregnancy and Risk of Preeclampsia or Gestational Hypertension

作者: Emily Oken , Yi Ning , Sheryl L. Rifas-Shiman , Janet W. Rich-Edwards , Sjurdur F. Olsen

DOI: 10.1016/J.ANNEPIDEM.2007.03.003

关键词: EndocrinologyBody mass indexInternal medicinePreeclampsiaEicosapentaenoic acidGestational hypertensionalpha-Linolenic acidMedicineDocosahexaenoic acidLower riskOdds ratioEpidemiology

摘要: Purpose We sought to examine associations of first-trimester intake calcium, n-3 and n-6 fatty acids, trans magnesium, folate, vitamins C, D, E with preeclampsia (PE) gestational hypertension (GH). Methods studied diet PE or GH among 1718 women in the prospective cohort study Project Viva, using logistic regression adjusting for maternal age, prepregnancy body mass index, first trimester systolic blood pressure, race/ethnicity, education, parity. assessed a validated semiquantitative food frequency questionnaire. Results A total 59 (3%) developed PE, 119 (7%) GH. found somewhat-lower risk associated higher elongated acids docosahexaenoic eicosapentaenoic (odds ratio [OR] 0.84, 95% confidence interval [95% CI]: 0.69–1.03 per 100 mg/day), fish (OR 0.91, CI 0.75–1.09 serving/day), + arachadonic acid 0.82, 0.66–1.01). did not observe lower greater calcium; vitamin E; milk; magnesium; folate; acids. Conclusions Our results support potential benefit preventing preeclampsia.

参考文章(37)
Francien V Velzing-Aarts, Fiona RM van der Klis, Fey PL van der Dijs, Frits AJ Muskiet, Umbilical vessels of preeclamptic women have low contents of both n−3 and n−6 long-chain polyunsaturated fatty acids The American Journal of Clinical Nutrition. ,vol. 69, pp. 293- 298 ,(1999) , 10.1093/AJCN/69.2.293
Baha M. Sibai, Prevention of preeclampsia: A big disappointment American Journal of Obstetrics and Gynecology. ,vol. 179, pp. 1275- 1278 ,(1998) , 10.1016/S0002-9378(98)70146-2
Jannie Dalby Salvig, Sjurdur F. Olsen, Niels Jsrgen Secher, Effects of fish oil supplementation in late pregnancy on blood pressure: a randomised controlled trial. British Journal of Obstetrics and Gynaecology. ,vol. 103, pp. 529- 533 ,(1996) , 10.1111/J.1471-0528.1996.TB09801.X
Dorothy Beazley, Robert Ahokas, Jeffrey Livingston, Mary Griggs, Baha M. Sibai, Vitamin C and E supplementation in women at high risk for preeclampsia: A double-blind, placebo-controlled trial American Journal of Obstetrics and Gynecology. ,vol. 192, pp. 520- 521 ,(2005) , 10.1016/J.AJOG.2004.09.005
Michelle A. Williams, Rosalee W. Zingheim, Irena B. King, Arthur M. Zebelman, Omega-3 fatty acids in maternal erythrocytes and risk of preeclampsia. Epidemiology. ,vol. 6, pp. 232- 237 ,(1995) , 10.1097/00001648-199505000-00007
Sjurour F. Olsen, Niels J. Secher, Ann Tabor, Tom Weber, James J. Walker, Christian Gluud, Randomised clinical trials of fish oil supplementation in high risk pregnancies British Journal of Obstetrics and Gynaecology. ,vol. 107, pp. 382- 395 ,(2000) , 10.1111/J.1471-0528.2000.TB13235.X
Michelle A. Williams, Irena B. King, Tanya K. Sorensen, Rosalee W. Zingheim, Barbara L. Troyer, Arthur M. Zebelman, David A. Luthy, Risk of Preeclampsia in Relation to Elaidic Acid (Trans Fatty Acid) in Maternal Erythrocytes Gynecologic and Obstetric Investigation. ,vol. 46, pp. 84- 87 ,(1998) , 10.1159/000010007
Alice R. Rumbold, Caroline A. Crowther, Ross R. Haslam, Gustaaf A. Dekker, Jeffrey S. Robinson, Vitamins C and E and the risks of preeclampsia and perinatal complications The New England Journal of Medicine. ,vol. 354, pp. 1796- 1806 ,(2006) , 10.1056/NEJMOA054186
Baha M. Sibai, Marco A. Villar L, Eileen Bray, Magnesium supplementation during pregnancy: a double-blind randomized controlled clinical trial. American Journal of Obstetrics and Gynecology. ,vol. 161, pp. 115- 119 ,(1989) , 10.1016/0002-9378(89)90246-9