作者: Emily Oken , Yi Ning , Sheryl L. Rifas-Shiman , Janet W. Rich-Edwards , Sjurdur F. Olsen
DOI: 10.1016/J.ANNEPIDEM.2007.03.003
关键词: Endocrinology 、 Body mass index 、 Internal medicine 、 Preeclampsia 、 Eicosapentaenoic acid 、 Gestational hypertension 、 alpha-Linolenic acid 、 Medicine 、 Docosahexaenoic acid 、 Lower risk 、 Odds ratio 、 Epidemiology
摘要: Purpose We sought to examine associations of first-trimester intake calcium, n-3 and n-6 fatty acids, trans magnesium, folate, vitamins C, D, E with preeclampsia (PE) gestational hypertension (GH). Methods studied diet PE or GH among 1718 women in the prospective cohort study Project Viva, using logistic regression adjusting for maternal age, prepregnancy body mass index, first trimester systolic blood pressure, race/ethnicity, education, parity. assessed a validated semiquantitative food frequency questionnaire. Results A total 59 (3%) developed PE, 119 (7%) GH. found somewhat-lower risk associated higher elongated acids docosahexaenoic eicosapentaenoic (odds ratio [OR] 0.84, 95% confidence interval [95% CI]: 0.69–1.03 per 100 mg/day), fish (OR 0.91, CI 0.75–1.09 serving/day), + arachadonic acid 0.82, 0.66–1.01). did not observe lower greater calcium; vitamin E; milk; magnesium; folate; acids. Conclusions Our results support potential benefit preventing preeclampsia.