[Animal models of human glioma: the progress of application and investigation].
作者： Hui-Fang ZHU , Yuan-Xu ZHANG , Xu-Dong ZHAO
DOI: 10.3724/SP.J.1141.2012.03337
关键词: Human glioma 、 Immunology 、 Cancer research 、 Transgenic technology 、 Glioma 、 Glioblastoma 、 Biology 、 Tumor Stem Cells 、 Animal model
摘要: The glioma accounts for half of the central nervous tumors, among which glioblastoma multiforme (GBM) is one most aggressive and lethal brain tumors. difficulties in therapy indicate need appropriate animal models preclinical studies. Benefiting from development molecular biology, genetics, transgenic technology, variable have been established. These human are reviewed this paper.
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