Morphological and Structural Changes During the Yeast-to-Mold Conversion of Phialophora dermatitidis

作者: Karen B. Oujezdsky , Stanley N. Grove , Paul J. Szaniszlo

DOI: 10.1128/JB.113.1.468-477.1973

关键词: CytoplasmCell wallMicrobiologyBiochemistryYeastVacuoleHyphaPhialophoraElectron microscopeBiologyRibosomeMolecular biology

摘要: The details of the morphological and structural events occurring during yeast-to-mold conversion human pathogenic fungus Phialophora dermatitidis as seen by phase-contrast microscopy electron are described illustrated. Budding yeasts growing exponentially were observed to have thin walls a cytoplasm exhibiting characteristics rapidly cells including numerous mitochondria, abundant ribosomes, few vacuoles, little accumulation storage material. In contrast, thick-walled characterized less apparent or significantly fewer mitochondria ribosomes presence considerable amounts materials. Microscope observations revealed that only having prominent lipid bodies in their converted hyphal forms. Typically, yeast formed two number moniliform which turn often produced true hyphae. results indicated P. must acquire spore-like becoming accumulating endogenous substrate reserves before they convert produce

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