PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas

作者: Hongwu Zheng , Haoqiang Ying , Ruprecht Wiedemeyer , Haiyan Yan , Steven N. Quayle

DOI: 10.1016/J.CCR.2010.03.020

关键词: Cell biologySignal transductionWnt signaling pathwayOncogeneNeural stem cellTranscriptomeStem cellCellular differentiationBiologyCell cycle

摘要: A hallmark feature of glioblastoma is its strong self-renewal potential and immature differentiation state, which contributes to its plasticity and therapeutic resistance. Here, integrated …

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