Circadian clocks in the ovary
作者： Michael T. Sellix , Michael Menaker
DOI: 10.1016/J.TEM.2010.06.002
关键词: Circadian rhythm 、 Ovarian physiology 、 Circadian clock 、 Ovulation 、 Peripheral oscillators 、 CLOCK 、 Biology 、 Internal medicine 、 Reproductive biology 、 Neuroscience 、 Ovary 、 Endocrinology
摘要: Clock gene expression has been observed in tissues of the hypothalamic–pituitary–gonadal (HPG) axis. Whereas contribution hypothalamic oscillators to timing reproductive biology is well known, role peripheral like those ovary less clear. Circadian clocks might play a ovulation. Disruption clock ovarian cells or desynchrony between and circadian elsewhere body may contribute onset progression various pathologies. In this paper, we review evidence for function across number species offer novel perspective into normal physiology diseases that negatively affect fertility.
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