Cetuximab Shows Activity in Colorectal Cancer Patients With Tumors for Which FISH Analysis Does Not Detect an Increase in EGFR Gene Copy Number

作者: Antoine Italiano , Philippe Follana , François-Xavier Caroli , Jean-Luc Badetti , Daniel Benchimol

DOI: 10.1245/S10434-007-9667-2

关键词: Fluorescence in situ hybridizationColorectal cancerOncologyCetuximabEpidermal growth factor receptorSurgical oncologyMedicineCancerImmunohistochemistryInternal medicineMouse model of colorectal and intestinal cancer

摘要: … However, seven of nine patients with objective responses who were assessable by use of FISH, in their series, would be classified as FISH positive with our criteria because they had a …

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