Fecal microbial composition of ulcerative colitis and Crohn's disease patients in remission and subsequent exacerbation.

作者: Edgar S. Wills , Daisy M. A. E. Jonkers , Paul H. Savelkoul , Ad A. Masclee , Marieke J. Pierik

DOI: 10.1371/JOURNAL.PONE.0090981

关键词: GastroenterologyInternal medicineColitisMedicineColonoscopyUlcerative colitisCrohn's diseaseEnemaInflammatory bowel diseaseThiopurine methyltransferaseExacerbation

摘要: Background Limited studies have examined the intestinal microbiota composition in relation to changes in disease course of IBD over time. We aimed to study prospectively the fecal …

参考文章(52)
Les Dethlefsen, Sue Huse, Mitchell L Sogin, David A Relman, The Pervasive Effects of an Antibiotic on the Human Gut Microbiota, as Revealed by Deep 16S rRNA Sequencing PLoS Biology. ,vol. 6, pp. e280- ,(2008) , 10.1371/JOURNAL.PBIO.0060280
Sung Jae Shin, Michael T. Collins, Thiopurine Drugs Azathioprine and 6-Mercaptopurine Inhibit Mycobacterium paratuberculosis Growth In Vitro Antimicrobial Agents and Chemotherapy. ,vol. 52, pp. 418- 426 ,(2008) , 10.1128/AAC.00678-07
Gwen M.C. Masclee, John Penders, Marieke Pierik, Petra Wolffs, Daisy Jonkers, Enteropathogenic viruses: Triggers for exacerbation in IBD? A prospective cohort study using real-time quantitative polymerase chain reaction Inflammatory Bowel Diseases. ,vol. 19, pp. 124- 131 ,(2013) , 10.1002/IBD.22976
Nabeetha A. Nagalingam, Susan V. Lynch, Role of the microbiota in inflammatory bowel diseases. Inflammatory Bowel Diseases. ,vol. 18, pp. 968- 984 ,(2012) , 10.1002/IBD.21866
Byron P. Vaughn, Sveta Shah, Adam S. Cheifetz, The Role of Mucosal Healing in the Treatment of Patients With Inflammatory Bowel Disease Current Treatment Options in Gastroenterology. ,vol. 12, pp. 103- 117 ,(2014) , 10.1007/S11938-013-0008-1
Nicholas J Talley, Maria T Abreu, Jean-Paul Achkar, Charles N Bernstein, Marla C Dubinsky, Stephen B Hanauer, Sunanda V Kane, William J Sandborn, Thomas A Ullman, Paul Moayyedi, American College of Gastroenterology IBD Task Force, An evidence-based systematic review on medical therapies for inflammatory bowel disease. The American Journal of Gastroenterology. ,vol. 106, ,(2011) , 10.1038/AJG.2011.58
James Buchanan, Sarah Wordsworth, Tariq Ahmad, Angela Perrin, Severine Vermeire, Miquel Sans, Jenny Taylor, Derek Jewell, None, Managing the long term care of inflammatory bowel disease patients: The cost to European health care providers Journal of Crohn's and Colitis. ,vol. 5, pp. 301- 316 ,(2011) , 10.1016/J.CROHNS.2011.02.005
Michael Scharl, Gerhard Rogler, Inflammatory bowel disease pathogenesis: what is new? Current Opinion in Gastroenterology. ,vol. 28, pp. 301- 309 ,(2012) , 10.1097/MOG.0B013E328353E61E
Shadi Sepehri, Roman Kotlowski, Charles N. Bernstein, Denis O. Krause, Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease. Inflammatory Bowel Diseases. ,vol. 13, pp. 675- 683 ,(2007) , 10.1002/IBD.20101
Young-Do Nam, Mi-Ja Jung, Seong Woon Roh, Min-Soo Kim, Jin-Woo Bae, Comparative Analysis of Korean Human Gut Microbiota by Barcoded Pyrosequencing PLoS ONE. ,vol. 6, pp. e22109- ,(2011) , 10.1371/JOURNAL.PONE.0022109