The complex association between metabolic syndrome and male hypogonadism

摘要: Abstract Background The complex association between metabolic syndrome (MetS) and male hypogonadism is well established. A number of observational studies show that low testosterone associated with insulin resistance an increased risk for diabetes mellitus MetS in men. Aims To elucidate the hypogonadism, present epidemiological data on co-existence two comorbidities, enlighten underlying pathophysiology appraise effects supplementation therapy (TTh) lifestyle modifications body composition Materials Methods Systematic search to PubMed Medline databases publications reporting hypogonadism. Results Both have a high prevalence general population are frequently co-existing e.g. males diabetes. Accumulating evidence from animal human suggests involved pathogenesis as other way around. On hand, there favorable effect deficient men and/or mellitus. Conclusions Studies superior methodological characteristics needed order establish role